Multiparticulates: Transforming Oral Therapies Through Patient-Centric Design

Multiparticulates like pellets, beads, and minitabs offer versatile solutions to address diverse patient-centric needs across pediatrics, geriatrics, and special populations. By overcoming key challenges such as palatability, swallowability, dosing flexibility, pill burden, and dosing frequency, multiparticulate systems enable tailored drug delivery with improved compliance and therapeutic outcomes. This presentation will explore how taste masking, flexible formats, modified-release technologies, and combination designs collectively position multiparticulates as an innovative approach that combines convenience, flexibility, and patient-centric oral delivery.

Learning Objectives:

  • • Identify five major patient-centric challenges addressed by multiparticulate formulations: taste masking, swallowability, dosing flexibility, pill burden, and dosing frequency.
  • • Explain how multiparticulate platforms enable customized, age-appropriate, and easy-to-administer dosage forms.
  • • Evaluate formulation and process strategies (e.g., coating, layering, encapsulation) that enhance palatability, modified release, and support combination therapies.
  • • Review case studies demonstrating the utilization of multiparticulates in patient-centric therapies for pediatrics, geriatrics, and chronic disease management.

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