Harbour BioMed, a global biopharmaceutical company, has entered a long-term strategic collaboration with Yantai Lannacheng Biotechnology Co., Ltd. to jointly advance the development of next-generation radionuclide drug conjugates (RDCs).

Compared with conventional radiotherapy, RDCs utilize tumor antigen–specific ligands to deliver radionuclides directly to tumor lesions for targeted radiotherapy, thereby effectively reducing damage to surrounding healthy tissues. In contrast to antibody–drug conjugates (ADCs), the radionuclides in RDCs can also exert cytotoxic effects on neighboring tumor cells and the tumor microenvironment, even if those cells do not express the target antigen. This mechanism offers a potential advantage in overcoming tumor heterogeneity and drug resistance. In addition, this technology holds the potential to achieve theranostics—integrating both diagnosis and treatment.

“We are very pleased to establish a long-term strategic collaboration with Lannacheng to jointly advance the development of next-generation RDCs,” said Jingsong Wang, MD, PhD, Founder, Chairman, and CEO of Harbour BioMed. “This collaboration will deeply integrate Harbour BioMed’s expertise in antibody discovery with Lannacheng’s strengths in radiopharmaceutical R&D and commercialization, accelerating the development of more precise, effective and safe cancer therapies and bringing new hope to patients worldwide.”

Wu Xiaoming, General Manager of Lannacheng, added: “This collaboration will fully combine Lannacheng’s strengths in radiopharmaceutical R&D and commercialization and Harbour BioMed’s deep expertise in antibody discovery. Together, we aim to accelerate the development of more precise, effective, and safe cancer treatment therapies, bringing new hope to patients worldwide.”