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Cytiva Launches Fibro dT Platform

Offers a high-capacity solution for mRNA purification with chromatography cycle times under 15 minutes.

Cytiva has launched the fibro dT platform for mRNA capture and purification processes.

Fibro is a specially-designed material made from electrospun cellulose that helps capture and purify RNA. It’s made to a consistent quality standard, which helps reduce the loss of valuable RNA. Because of its unique structure and design, it can handle large amounts of RNA efficiently and speeds the purification process by avoiding the need for the RNA to move into tiny resin beads.

Emmanuel Abate, President of Genomic Medicine at Cytiva, said: “The industry has long sought efficient methods to capture valuable molecules, minimizing waste and maximizing yield. Fibro dT achieves this quickly and cost-effectively, ultimately benefitting patients in need of advanced therapies.”

Key features include:

  • 6 mg/mL mRNA binding capacity (typical 2000‑mer with poly(A) tail)
  • < 15 minutes per chromatography cycle (0.4 mL unit)
  • High reproducibility across cycles and batches
  • Engineered for lower‑salt loading, helping limit precipitation risk and improve impurity clearance
  • ÄKTA‑compatible workflows for streamlined setup and training

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