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Genen will oversee Medical and Clinical Affairs, lead the company’s clinical strategy, and champion adoption of genomic medicine.
January 6, 2026
By: Charlie Sternberg
GeneDx, a rare disease diagnosis company, has appointed Linda Genen, MD, MPH as Chief Medical Officer to strengthen the company’s commitment to delivering earlier answers and better outcomes for families through genomic insights.
Genen will oversee Medical and Clinical Affairs, lead the company’s clinical strategy, and champion adoption of genomic medicine across health systems, payers, policymakers, and the broader medical community. She will work closely with GeneDx’s executive team to accelerate integration of genomics into routine care and ensure that families everywhere benefit from earlier diagnosis and intervention. Genen will also help shape the company’s real-world evidence initiatives, guide payer engagement, and partner closely across GeneDx’s innovation, commercial, and policy teams to advance adoption of genomic medicine at scale.
Katherine Stueland, President and CEO of GeneDx, said, “Dr. Genen has a passion for how genomics can and should be used to improve health outcomes for everyone. Her deep clinical experience, payer expertise, and proven ability to drive innovation at scale make her uniquely equipped to help lead the next chapter of genomic adoption and patient impact. By incorporating exome and genome testing at the earliest moment possible, we can transform our approach to healthcare.”
Genen brings decades of leadership across clinical practice, payer strategy, innovation, and maternal-infant health. A former neonatologist and healthcare executive, she joins GeneDx from ProgenyHealth, a national, tech-enabled women’s healthcare company dedicated to maternity and NICU care management, where she served as Chief Medical Officer and led clinical strategy, analytics, and quality programs that improved outcomes for mothers and infants across diverse populations.
Genen previously held senior leadership roles at UnitedHealth Group and Optum, where she developed and scaled innovative models in women’s health, digital care delivery, and maternal-infant medicine. Earlier in her career, she served as a practicing neonatologist at Northwell’s Cohen Children’s Hospital and Assistant Professor of Pediatrics at Hofstra University. She currently serves on the board of Hera Women’s Health and is a Distinguished Mentor in Stanford University’s Clinical Informatics Management program.
GeneDx also recently named a new Chief Precision Medicine Officer and Chief Business Officer.
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